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Darren R. Flower
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2020 – today
- 2023
- [j41]Subhagata Chattopadhyay, Nhat Phuong Do, Darren R. Flower, Amit K. Chattopadhyay
:
Extracting prime protein targets as possible drug candidates: machine learning evaluation. Medical Biol. Eng. Comput. 61(11): 3035-3048 (2023) - 2020
- [j40]Monica J. Quinzo
, Esther M. Lafuente, Pilar Zuluaga, Darren R. Flower, Pedro A. Reche
:
Correction to: Computational assembly of a human Cytomegalovirus vaccine upon experimental epitope legacy. BMC Bioinform. 21(1): 116 (2020)
2010 – 2019
- 2019
- [j39]Monica J. Quinzo
, Esther M. Lafuente
, Pilar Zuluaga, Darren R. Flower, Pedro A. Reche
:
Computational assembly of a human Cytomegalovirus vaccine upon experimental epitope legacy. BMC Bioinform. 20-S(6): 476 (2019) - 2018
- [c4]Monica J. Quinzo
, Esther M. Lafuente
, Pedro A. Reche
, Darren R. Flower:
Computational design of a legacy-based epitope vaccine against Human Cytomegalovirus. BIBM 2018: 1411-1417 - 2016
- [j38]Enrique Audain
, Yassel Ramos
, Henning Hermjakob
, Darren R. Flower, Yasset Pérez-Riverol
:
Accurate estimation of isoelectric point of protein and peptide based on amino acid sequences. Bioinform. 32(6): 821-827 (2016) - [j37]Qamar M. Sheikh, Derek Gatherer
, Pedro A. Reche
, Darren R. Flower:
Towards the knowledge-based design of universal influenza epitope ensemble vaccines. Bioinform. 32(21): 3233-3239 (2016) - 2015
- [j36]Egle Bunkute, Christopher Cummins, Fraser J. Crofts
, Gareth Bunce, Ian T. Nabney
, Darren R. Flower:
PIP-DB: the Protein Isoelectric Point database. Bioinform. 31(2): 295-296 (2015) - [j35]Amit K. Chattopadhyay
, Diar Nasiev, Darren R. Flower:
A statistical physics perspective on alignment-independent protein sequence comparison. Bioinform. 31(15): 2469-2474 (2015) - 2014
- [c3]Shahzad Mumtaz, Darren R. Flower, Ian T. Nabney:
Multi-level Visualisation using Gaussian Process Latent Variable Models. IVAPP 2014: 122-129 - 2013
- [j34]Ivan Dimitrov
, Darren R. Flower, Irini A. Doytchinova
:
AllerTOP - a server for in silico prediction of allergens. BMC Bioinform. 14(S-6): S4 (2013) - 2012
- [c2]Shahzad Mumtaz
, Ian T. Nabney, Darren R. Flower:
Novel visualization methods for protein data. CIBCB 2012: 198-205 - 2010
- [j33]Ivan Dimitrov
, Panayot Garnev, Darren R. Flower, Irini A. Doytchinova
:
EpiTOP - a proteochemometric tool for MHC class II binding prediction. Bioinform. 26(16): 2066-2068 (2010) - [j32]Andrew Secker, Matthew N. Davies, Alex Alves Freitas
, Edward Clark, Jonathan Timmis
, Darren R. Flower:
Hierarchical classification of G-Protein-Coupled Receptors with data-driven selection of attributes and classifiers. Int. J. Data Min. Bioinform. 4(2): 191-210 (2010) - [j31]Hifzur Rahman Ansari, Darren R. Flower, G. P. S. Raghava
:
AntigenDB: an immunoinformatics database of pathogen antigens. Nucleic Acids Res. 38(Database-Issue): 847-853 (2010)
2000 – 2009
- 2009
- [j30]Andrew Secker, Matthew N. Davies, Alex Alves Freitas, Jonathan Timmis
, Edward Clark, Darren R. Flower:
An Artificial Immune System for Clustering Amino Acids in the Context of Protein Function Classification. J. Math. Model. Algorithms 8(2): 103-123 (2009) - 2008
- [j29]Matthew N. Davies, Andrew Secker, Alex Alves Freitas
, Edward Clark, Jonathan Timmis
, Darren R. Flower:
Optimizing amino acid groupings for GPCR classification. Bioinform. 24(18): 1980-1986 (2008) - [c1]Andrew Secker, Matthew N. Davies, Alex Alves Freitas
, Jonathan Timmis
, Edward Clark, Darren R. Flower:
An Artificial Immune System for Evolving Amino Acid Clusters Tailored to Protein Function Prediction. ICARIS 2008: 242-253 - 2007
- [j28]Matthew N. Davies, Andrew Secker, Alex Alves Freitas
, Miguel Mendao, Jonathan Timmis
, Darren R. Flower:
On the hierarchical classification of G protein-coupled receptors. Bioinform. 23(23): 3113-3118 (2007) - [j27]Irini A. Doytchinova
, Darren R. Flower:
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines. BMC Bioinform. 8 (2007) - [j26]Irini A. Doytchinova
, Darren R. Flower:
Predicting Class I Major Histocompatibility Complex (MHC) Binders Using Multivariate Statistics: Comparison of Discriminant Analysis and Multiple Linear Regression. J. Chem. Inf. Model. 47(1): 234-238 (2007) - 2006
- [j25]Irini A. Doytchinova
, Pingping Guan, Darren R. Flower:
EpiJen: a server for multistep T cell epitope prediction. BMC Bioinform. 7: 131 (2006) - [j24]Wen Liu, Xiangshan Meng, Qiqi Xu
, Darren R. Flower, Tongbin Li:
Quantitative prediction of mouse class I MHC peptide binding affinity using support vector machine regression (SVR) models. BMC Bioinform. 7: 182 (2006) - [j23]Ji Wan
, Wen Liu, Qiqi Xu
, Yongliang Ren, Darren R. Flower, Tongbin Li:
SVRMHC prediction server for MHC-binding peptides. BMC Bioinform. 7: 463 (2006) - [j22]Jesper Salomon, Darren R. Flower:
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores. BMC Bioinform. 7: 501 (2006) - [j21]Channa K. Hattotuwagama, Christopher P. Toseland
, Pingping Guan, Debra J. Taylor, Shelley L. Hemsley, Irini A. Doytchinova
, Darren R. Flower:
Toward Prediction of Class II Mouse Major Histocompatibility Complex Peptide Binding Affinity: in Silico Bioinformatic Evaluation Using Partial Least Squares, a Robust Multivariate Statistical Technique. J. Chem. Inf. Model. 46(3): 1491-1502 (2006) - [j20]Christopher P. Toseland
, Helen M. McSparron, Matthew N. Davies, Darren R. Flower:
PPD v1.0 - an integrated, web-accessible database of experimentally determined protein pKa values. Nucleic Acids Res. 34(Database-Issue): 199-203 (2006) - 2005
- [j19]Christopher P. Toseland
, Helen M. McSparron, Darren R. Flower:
DSD - An integrated, web-accessible database of Dehydrogenase Enzyme Stereospecificities. BMC Bioinform. 6: 283 (2005) - [j18]Irini A. Doytchinova
, Valerie Walshe, Persephone Borrow
, Darren R. Flower:
Towards the chemometric dissection of peptide - HLA-A*0201 binding affinity: comparison of local and global QSAR models. J. Comput. Aided Mol. Des. 19(3): 203-212 (2005) - [j17]Channa K. Hattotuwagama, Irini A. Doytchinova
, Darren R. Flower:
In Silico Prediction of Peptide Binding Affinity to Class I Mouse Major Histocompatibility Complexes: A Comparative Molecular Similarity Index Analysis (CoMSIA) Study. J. Chem. Inf. Model. 45(5): 1415-1423 (2005) - 2004
- [j16]Shunzhou Wan, Peter V. Coveney, Darren R. Flower:
Large-scale molecular dynamics simulations of HLA-A*0201 complexed with a tumor-specific antigenic peptide: Can the α3 and β2m domains be neglected? J. Comput. Chem. 25(15): 1803-1813 (2004) - 2003
- [j15]Irini A. Doytchinova
, Darren R. Flower:
Towards the in silico identification of class II restricted T-cell epitopes: a partial least squares iterative self-consistent algorithm for affinity prediction. Bioinform. 19(17): 2263-2270 (2003) - [j14]Helen M. McSparron, Martin J. Blythe, Christianna Zygouri, Irini A. Doytchinova
, Darren R. Flower:
JenPep: A Novel Computational Information Resource for Immunobiology and Vaccinology. J. Chem. Inf. Comput. Sci. 43(4): 1276-1287 (2003) - [j13]Terri K. Attwood
, Paul Bradley, Darren R. Flower, Anna Gaulton
, Neil Maudling, Alex L. Mitchell
, G. Moulton, A. Nordle, K. Paine, P. Taylor, A. Uddin, Christianna Zygouri:
PRINTS and its automatic supplement, prePRINTS. Nucleic Acids Res. 31(1): 400-402 (2003) - [j12]Pingping Guan, Irini A. Doytchinova
, Christianna Zygouri, Darren R. Flower:
MHCPred: a server for quantitative prediction of peptide-MHC binding. Nucleic Acids Res. 31(13): 3621-3624 (2003) - [j11]Paul D. Taylor, Terri K. Attwood
, Darren R. Flower:
BPROMPT: a consensus server for membrane protein prediction. Nucleic Acids Res. 31(13): 3698-3700 (2003) - 2002
- [j10]Martin J. Blythe, Irini A. Doytchinova
, Darren R. Flower:
JenPep: a database of quantitative functional peptide data for immunology. Bioinform. 18(3): 434-439 (2002) - [j9]Irini A. Doytchinova
, Darren R. Flower:
A Comparative Molecular Similarity Index Analysis (CoMSIA) study identifies an HLA-A2 binding supermotif. J. Comput. Aided Mol. Des. 16(8-9): 535-544 (2002) - [j8]Christian Schönbach
, Judice L. Y. Koh, Darren R. Flower, Limsoon Wong
, Vladimir Brusic
:
FIMM, a database of functional molecular immunology: update 2002. Nucleic Acids Res. 30(1): 226-229 (2002) - [j7]Terri K. Attwood
, Martin J. Blythe, Darren R. Flower, Anna Gaulton
, J. E. Mabey, Neil Maudling, L. McGregor, Alex L. Mitchell
, G. Moulton, K. Paine, Philip Scordis
:
PRINTS and PRINTS-S shed light on protein ancestry. Nucleic Acids Res. 30(1): 239-241 (2002) - 2000
- [j6]Terri K. Attwood
, Michael D. R. Croning, Darren R. Flower, A. P. Lewis, J. E. Mabey, Philip Scordis
, J. N. Selley, W. Wright:
PRINTS-S: the database formerly known as PRINTS. Nucleic Acids Res. 28(1): 225-227 (2000)
1990 – 1999
- 1999
- [j5]Philip Scordis
, Darren R. Flower, Terri K. Attwood:
FingerPRINTScan: intelligent searching of the PRINTS motif database. Bioinform. 15(10): 799-806 (1999) - [j4]Terri K. Attwood
, Darren R. Flower, A. P. Lewis, J. E. Mabey, S. R. Morgan, Philip Scordis
, J. N. Selley, W. Wright:
PRINTS prepares for the new millennium. Nucleic Acids Res. 27(1): 220-225 (1999) - 1998
- [j3]Darren R. Flower:
On the Properties of Bit String-Based Measures of Chemical Similarity. J. Chem. Inf. Comput. Sci. 38(3): 379-386 (1998) - [j2]Terri K. Attwood, Michael E. Beck, Darren R. Flower, Philip Scordis
, J. N. Selley:
The PRINTS protein fingerprint database in its fifth year. Nucleic Acids Res. 26(1): 304-308 (1998) - 1997
- [j1]Terri K. Attwood
, H. Avison, Michael E. Beck, Maria C. Bewley
, Alan J. Bleasby, F. Brewster, P. Cooper, Kirill Degtyarenko, A. J. Geddes, Darren R. Flower, M. P. Kelly, Shaun Lott, K. M. Measures, David J. Parry-Smith, D. N. Perkins, Philip Scordis
, David Scott, C. Worledge:
The PRINTS Database of Protein Fingerprints: A Novel Information Resource for Computational Molecular Biology. J. Chem. Inf. Comput. Sci. 37(3): 417-424 (1997)
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