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ORCIDQuantitative Biology, Volume 9
Volume 9, Number 1, 2021
- Xuegong Zhang:
Featured articles dedicated to the 20th anniversary of the human genome. 1 - Michael S. Waterman:
The Human Genome Project: the Beginning of the Beginning. 4 - Michael Q. Zhang:
A personal journey on cracking the genomic codes. 8 - Wanyu Tao, Zhengqing Yu
, Jing-Dong J. Han:
A digitized catalog of COVID-19 epidemiology data. 23 - Fengyu Zhang, Yanhong Sun, Chunxiong Luo:
Microfluidic approaches for synthetic gene circuits' construction and analysis. 47 - Cecylia S. Lupala, Xuanxuan Li, Jian Lei, Hong Chen, Jianxun Qi, Haiguang Liu, Xiao-dong Su:
Computational simulations reveal the binding dynamics between human ACE2 and the receptor binding domain of SARS-CoV-2 spike protein. 61 - Guanyu Wang:
Testing the leanocentric locking-point theory by in silico partial lipectomy. 73 - Saroj K. Biswas, Nasir U. Ahmed:
Mathematical modeling and optimal intervention of COVID-19 outbreak. 84 - Yuehui Zhang, Lin Chen, Qili Shi, Zhongguang Luo, Libing Shen:
Forecasting the development of the COVID-19 epidemic by nowcasting: when did things start to get better? 93 - Shuguang Peng, Huiya Huang, Ping Wei, Zhen Xie:
Synthetic gene circuits moving into the clinic. 100 - Lin Hou, Qiongshi Lu, Can Yang, Hongyu Zhao:
Special issue on genome wide association study. 105-106 - Huanhuan Zhu, Xiang Zhou:
Transcriptome-wide association studies: a view from Mendelian randomization. 107-121 - Xiaofeng Zhu:
Mendelian randomization and pleiotropy analysis. 122-132 - Zijie Zhao, Jie Song, Tuo Wang, Qiongshi Lu:
Polygenic risk scores: effect estimation and model optimization. 133-140 - Yuhan Xie, Nayang Shan, Hongyu Zhao, Lin Hou:
Transcriptome wide association studies: general framework and methods. 141-150 - Xu Liao, Xiaoran Chai, Xingjie Shi, Lin S. Chen, Jin Liu:
The statistical practice of the GTEx Project: from single to multiple tissues. 151-167 - Hua Tang, Zihuai He:
Advances and challenges in quantitative delineation of the genetic architecture of complex traits. 168-184 - Katherine A. Knutson, Wei Pan:
Integrating brain imaging endophenotypes with GWAS for Alzheimer's disease. 185-200 - Kang Kang, Xue Sun, Lizhong Wang, Xiaotian Yao, Senwei Tang, Junjie Deng, Xiaoli Wu, Wegene Research Team, Can Yang, Gang Chen:
Direct-to-consumer genetic testing in China and its role in GWAS discovery and replication. 201-215 - Mo Li, Xue Zeng, Chentian Jin, Sheng Chih Jin, Weilai Dong, Martina Brueckner, Richard Lifton, Qiongshi Lu, Hongyu Zhao:
Integrative modeling of transmitted and de novo variants identifies novel risk genes for congenital heart disease. 216-227
Volume 9, Number 3, September 2021
- Wei Dong, Boqing Qiang, Huanming Yang:
The international Human Genome Project: A milestone for life sciences and humanity-The three stages and three major impacts of the HGP, and three contributions by China. 229-241 - Runsheng Chen:
Early bioinformatics research in China. 242-250 - Andrew F. Neuwald:
Reflections on the quest to obtain biological information from genomic data. 251-254 - Taoyu Chen, Qi Lei, Minglei Shi, Tingting Li:
High-throughput experimental methods for investigating biomolecular condensates. 255-266 - Tianying Chen, Xue Zhang, Qiong Wu:
Recent progress in research and application of engineered implanted cells for biomedical applications. 267-291 - Lei Zhang, Ji Lv, Ming Xiao, Li Yang, Le Zhang:
Exploring the underlying mechanism of action of a traditional Chinese medicine formula, Youdujing ointment, for cervical cancer treatment. 292-303 - Shilei Zhao, Tong Sha, Chung-i Wu, Yongbiao Xue, Hua Chen:
Will the large-scale vaccination succeed in containing the COVID-19 pandemic and how soon? 304-316 - Rudra Banerjee, Srijit Bhattacharjee, Pritish Kumar Varadwaj:
A study of the COVID-19 epidemic in India using the SEIRD model. 317-328 - Zongwei Guo, Fangkui Yin, Peiran Wang, Ting Song, Zhichao Zhang:
Systems analysis of the "weights" of Bcl-2 and Mcl-1 in mitochondrial apoptosis pathway establishes a predictor for best drug combination ratio. 329-340 - Eric Durandau, Serge Pelet:
Cross-regulation between CDK and MAPK control cellular fate. 341-359
Volume 9, Number 4, December 2021
- Jinghui Zhang:
Mapping genetic variations in the first assembled human genome. 361-365 - Zhaohui S. Qin:
A wonderful time - exciting progress made in the past 20 years in genetics powered by the Human Genome Project. 366-370 - Hongyu Zhao:
Roles of statistical modeling in characterizing the genetic basis of human diseases and traits. 371-377 - Shi Shuyu, Si Wen, Ouyang Xiaoyi, Wei Ping:
Phase separation in synthetic biology. 378-399 - Ben P. Tatman, Thomas Mock, Taoyang Wu, Cock van Oosterhout:
Significance of differential allelic expression in phenotypic plasticity and evolutionary potential of microbial eukaryotes. 400-410 - Jing Tang, Yongheng Wang, Jianbo Fu, Xianglu Wu, Zhijie Han, Chuan Wang, Maiyuan Guo, Yingxiong Wang, Yubin Ding, Bo Yang, Feng Zhu:
Functional characterization of disease/comorbidity-associated lncRNA. 411-425 - Xiao-Ying Yan, Shaowu Zhang, Siu-Ming Yiu, Jian-Yu Shi:
Interpretable prediction of drug-cell line response by triple matrix factorization. 426-439 - Pavel Pronkin, Alexander Tatikolov:
Molecular docking of cyanine and squarylium dyes with SARS-CoV-2 proteases NSP3, NSP5 and NSP12. 440-450 - Ya-li Zhu, Xiao-ning Zhang, Chuan-Yuan Wang, Jin-Xing Liu, Xiangzhen Kong:
Adaptive total variation constraint hypergraph regularized NMF for single-cell RNA-seq data analysis. 451-462
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