How accurate and statistically robust are catalytic site predictions based on closeness centrality?

Eric Chea Dennis R. Livesay How accurate and statistically robust are catalytic site predictions based on closeness centrality? 2007 8 BMC Bioinformatics http://dx.doi.org/10.1186/1471-2105-8-153 db/journals/bmcbi/bmcbi8.html#CheaL07