Facilitating Transformations in a Human Genome Project Database.

Susan B. Davidson, Anthony Kosky, Barbara A. Eckman: Facilitating Transformations in a Human Genome Project Database. CIKM 1994: 423-432

@inproceedings{DBLP:conf/cikm/DavidsonKE94,
  author    = {Susan B. Davidson and
               Anthony Kosky and
               Barbara A. Eckman},
  title     = {Facilitating Transformations in a Human Genome Project Database},
  booktitle = {Proceedings of the Third International Conference on Information
               and Knowledge Management (CIKM'94), Gaithersburg, Maryland, November
               29 - December 2, 1994},
  publisher = {ACM},
  year      = {1994},
  pages     = {423-432},
  ee        = {db/conf/cikm/DavidsonKE94.html, http://doi.acm.org/10.1145/191246.191317},
  crossref  = {DBLP:conf/cikm/94},
  bibsource = {DBLP, http://dblp.uni-trier.de}
}

Abstract

Human Genome Project databases present a confluence of interesting database challenges: rapid schema and data evolution, complex data entry and constraint management, and the need to integrate multiple data sources and software systems which range over a wide variety of models and formats. While these challenges are not necessarily unique to biological databases, their combination, intensity and complexity are unusual and make automated solutions imperative. We illustrate these problems in the context of the Philadelphia Genome Center for Human Chromosome 22, and describe a new approach to a solution for these problems, by means of a deductive language for expressing database transformations and constraints.

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Proceedings of the Third International Conference on Information and Knowledge Management (CIKM'94), Gaithersburg, Maryland, November 29 - December 2, 1994. ACM 1994
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